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human normal lung fibroblast cell line mrc9  (ATCC)


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    ATCC human normal lung fibroblast cell line mrc9
    Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of <t>MRC9</t> cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.
    Human Normal Lung Fibroblast Cell Line Mrc9, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 120 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human normal lung fibroblast cell line mrc9/product/ATCC
    Average 95 stars, based on 120 article reviews
    human normal lung fibroblast cell line mrc9 - by Bioz Stars, 2026-03
    95/100 stars

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    1) Product Images from "PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity"

    Article Title: PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity

    Journal: bioRxiv

    doi: 10.1101/2025.02.19.638860

    Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of MRC9 cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.
    Figure Legend Snippet: Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of MRC9 cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.

    Techniques Used: Two Tailed Test, Western Blot, Expressing



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    human normal lung fibroblast cell line mrc9  (ATCC)
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    ATCC human normal lung fibroblast cell line mrc9
    Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of <t>MRC9</t> cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.
    Human Normal Lung Fibroblast Cell Line Mrc9, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human normal lung fibroblast cell line mrc9/product/ATCC
    Average 95 stars, based on 1 article reviews
    human normal lung fibroblast cell line mrc9 - by Bioz Stars, 2026-03
    95/100 stars
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    Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of MRC9 cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.

    Journal: bioRxiv

    Article Title: PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity

    doi: 10.1101/2025.02.19.638860

    Figure Lengend Snippet: Quantification and representative images of clonogenic survival analysis of H460 ( A ) and A549 ( B ) cells treated with CFI-400945 (10nM). Error bars represent standard error of the mean (SEM) for n=3 independent experiments analyzed by unpaired, two-tailed t-tests. Clonogenic survival analysis of H460 ( C ) or A549 ( D ) cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. Clonogenic survival analysis of H460 ( E ) or A549 ( F ) cells treated with vehicle (DMSO) or centrinone (2.5 µM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM analyzed by two-way ANOVA testing. G. Clonogenic survival analysis of MRC9 cells treated with vehicle (DMSO) or CFI-400945 (10nM) and the indicated dose of radiation. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± SEM. H. Immunoblot of PLK4 expression in the indicated cell lines. Immunoblots are representative of three independent experiments.

    Article Snippet: The human NSCLC cell lines H460 and A549, and human normal lung fibroblast cell line MRC9 were purchased from American Type Culture Collection (ATCC).

    Techniques: Two Tailed Test, Western Blot, Expressing